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CeraVe Itch Relief Cream for Bedtime Skincare – Fast-Acting Soothing Moisturizer for Peaceful Sleep

CeraVe Itch Relief Cream for Bedtime Skincare – Fast-Acting Soothing Moisturizer for Peaceful Sleep

Regular price $31.16 USD
Regular price $45.54 USD Sale price $31.16 USD -32%
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Why you'll love it

  • clinically proven relief within 2 minutes lasting up to 8 hours eliminates need for repeated reapplication
  • steroid-free formula makes it safe for long-term use and suitable for sensitive skin
  • dual action as both anti-itch treatment and moisturizer replaces two separate products
  • NEA Seal of Acceptance builds trust for eczema sufferers seeking dermatologist-backed options
  • fragrance-free and non-comedogenic formula reduces risk of further skin irritation
  • FSA and HSA eligibility lowers out-of-pocket cost and positions it as a medical-grade solution

Perfect for

  • applying after bug bites during outdoor activities to stop itching fast
  • soothing sunburned skin after beach or pool exposure
  • managing eczema-related itch flare-ups as part of daily skincare routine
  • treating poison ivy or contact irritation after yard work or hiking
  • using as an FSA/HSA-eligible medicated moisturizer for ongoing dry and itchy skin

Developed with dermatologists, CeraVe has a complete line of skincare to cleanse and moisturize skin. CeraVe contains the three essential ceramides (called 1, 3, and 6-II) healthy skin needs. Delivered through a controlled-release technology, this formula with ceramides helps rebuild the skin's protective barrier and locks in moisture all day.

Itch Relief Moisturizing Cream

Product Technology

Developed with dermatologists and formulated with the anti-itch ingredient, Pramoxine Hydrochloride 1%, CeraVe Itch Relief Moisturizing Cream temporarily relieves itching associated with minor skin irritations, insect bites and sunburn. The product also contains three essential ceramides that helps repair and restore the skin’s barrier all in an emollient based cream with a rich, velvety texture.


How to Use

Apply to affected area no more than 3 to 4 times daily.


Clinically Tested

100% of people experienced relief for even their most severe itch.*

*Clinical study of 34 subjects. Individual results may vary.


Fast Acting

2 minutes until relief for most people*

*Clinical study of 34 subjects. Individual results may vary.


Long Lasting

8 hours of relief for most people*

*Clinical study of 34 subjects. Individual results may vary.


3 Essential Ceramides

All CeraVe products contain the vital ceramides healthy skin needs to help restore and maintain its natural protective barrier.


The Role of Ceramides

Ceramides are an essential part of the skin's natural barrier. They hydrate all day to help restore the protective skin barrier.


Developed with Dermatologists

CeraVe Itch Relief Moisturizing Cream temporarily relieves itch due to insect bites, sunburn and minor skin irritations.


NEA Seal of Acceptance

The National Eczema Association Seal of Acceptance only accepts products that have satisfied the criteria for use for those with eczema or sensitive skin conditions.

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The CeraVe story began in 2005 after experts noticed that many skin conditions such as acne, eczema, psoriasis and dry skin all had one thing in common: a compromised skin barrier. Developed with dermatologists, CeraVe offers a complete line of skincare & haircare products that contain three essential ceramides enhanced with a revolutionary delivery system to help restore the skin & scalp's natural protective barrier.


Product Information
[ CERAVE ANTI ITCH CREAM ] Temporarily relieves itching associated with insect bites, sunburn, poison ivy while moisturizing dry skin. Rich, velvety texture that is absorbed quickly for softened skin with non-greasy feel.

[ CLINICALLY TESTED ] Provides relief within two minutes and lasts up to 8 hours. 100 percent of people experienced relief for even their most severe itch; clinical study done on 34 subjects. Individual results may vary.

[ SOOTHING INGREDIENTS ] Formulated with 1% Pramoxine Hydrochloride for fast-acting, long-lasting temporary itch-relief, Niacinamide to help calm skin, and Hyaluronic Acid to help retain skin’s natural moisture.

[ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) to help restore and maintain the skin’s natural barrier

[ DEVELOPED WITH DERMATOLOGISTS ] Suitable for use on face, body, and hands to temporarily relieve itching. Holds National Eczema Association (NEA) Seal of Acceptance. Fragrance free, steroid-free, and non-comedogenic. FSA Eligible & HSA Eligible
Developed with dermatologists, CeraVe Itch Relief Moisturizing Cream temporarily relieves itching associated with minor skin irritations, insect bites and sunburn. Formulated with anti-itch ingredient Pramoxine Hydrochloride 1%, this body cream provides fast-acting, long-lasting itch relief. The product also contains three essential ceramides that helps repair and restore the skin’s barrier all in an emollient-based cream with a rich, velvety texture.

Items Details

Frequently Asked Questions

Does the pramoxine hydrochloride in this cream provide fast relief so I can relax into my bedtime routine?

Yes! The 1% pramoxine hydrochloride works within 2 minutes to stop itching, allowing you to complete your skincare ritual without interruption. Relief lasts up to 8 hours, so you can drift into sleep peacefully without the urge to scratch.

Will this cream absorb quickly enough that it won't feel heavy or sticky during my evening self-care routine?

Absolutely. The formula features a non-greasy, velvety texture that absorbs quickly into skin, making it perfect for nighttime routines. It feels luxurious but won't leave your skin feeling weighed down or uncomfortable.

Since this is fragrance-free, will it work just as well for calming irritated skin as scented moisturizers?

Yes, it's actually better for sensitive skin. The fragrance-free formula eliminates a common irritant, while ceramides, hyaluronic acid, and niacinamide work together to calm and soothe. Many people find the absence of fragrance itself enhances their relaxation ritual.

Can I use this as my daily moisturizer as part of a wellness-focused skincare regimen, or is it only for acute itching?

It works beautifully as both. The dual-action formula—combining itch relief with moisturizing ceramides and hyaluronic acid—makes it ideal for daily use. Many wellness-focused users incorporate it into morning and evening routines for ongoing skin health.

Does the 16-ounce size last long enough to make this a staple in my daily self-care routine?

Yes. The large 16-ounce size is designed for extended household use, making it economical for daily application on face, body, and hands. Most customers find it lasts several months with regular use, justifying its place in a wellness routine.

How should I apply this itch relief cream for best results?

Apply a thin layer directly to the affected area and gently massage until fully absorbed. For itch relief, apply as needed. For daily eczema management, use twice daily (morning and evening) or as directed by a dermatologist. The non-greasy formula absorbs within minutes, so you can apply makeup or clothing immediately afterward.

Can I use this cream on my entire body, or is it only for specific areas?

You can use it anywhere on your body—face, hands, arms, legs, and sensitive areas. The gentle formula makes it suitable for all skin types. Many users apply it to multiple problem areas throughout the day and as part of their daily moisturizing routine.

How does this cream compare to hydrocortisone creams or other medicated itch treatments?

Unlike hydrocortisone (a steroid), this cream is steroid-free, making it safer for long-term use without the risk of skin thinning or dependency. While hydrocortisone works on inflammatory itch, this formula combines pramoxine for immediate itch relief with ceramides and humectants for skin barrier repair—offering both symptom relief and lasting skin health benefits.

What comes in the box, and do I need to buy anything separately?

The package includes one 16-ounce jar of CeraVe Itch Relief Cream. The jar comes ready to use—no setup required. If you're taking it traveling, you may want to purchase a small travel jar or container to decant a portion, but the product itself needs nothing else.

Is this product safe if I'm pregnant or breastfeeding?

Pramoxine hydrochloride is minimally absorbed through the skin and is generally considered safe during pregnancy and breastfeeding, but consult your OB-GYN or dermatologist before use, especially if applying to large body areas. The ceramides and hyaluronic acid are pregnancy-safe skincare ingredients used widely by expectant mothers.

Will this cream stain clothing or leave residue?

No. The non-greasy, quickly absorbed formula won't stain fabrics. It dries to a matte finish within minutes, so you can apply it and dress immediately. Unlike heavier creams or ointments, this won't transfer to clothing or bedding.

How long does the 16-ounce jar typically last with daily use?

Usage varies by application amount and body surface area treated, but most customers find a 16-ounce jar lasts 2–4 months with twice-daily application to face and body. If using it solely for spot treatment of bug bites or eczema patches, it may last longer.

Can I use this if I have very sensitive or reactive skin prone to allergies?

Yes, this is specifically formulated for sensitive skin. It's hypoallergenic, fragrance-free, non-comedogenic, and has the NEA Seal of Acceptance. However, if you have a known allergy to pramoxine or any listed ingredients, avoid it. When in doubt, do a patch test or consult your dermatologist.

What's the difference between this itch cream and a regular moisturizer?

Regular moisturizers hydrate skin but don't address itching. This cream combines a medicated itch reliever (pramoxine) with moisturizing ingredients (ceramides, hyaluronic acid, niacinamide). It stops active itching within 2 minutes while repairing the skin barrier—making it both treatment and prevention in one product.

How should I store this cream to maintain its effectiveness?

Store at room temperature in a cool, dry place away from direct sunlight and heat. Keep the jar tightly closed after each use to prevent moisture loss. Avoid storing in bathrooms with extreme humidity if possible, as excess moisture can affect texture. When stored properly, the formula remains effective for its full shelf life.

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